Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. 23847046

2013
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. 23792957

2013
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013
dbSNP: rs28938172
rs28938172
PARK7
0.800 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. 23847046

2013
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. 23792957

2013
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. 23847046

2013
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. 23279440

2013
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. 23792957

2013
dbSNP: rs774005786
rs774005786
PARK7
0.700 GeneticVariation UNIPROT Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. 23792957

2013
dbSNP: rs774005786
rs774005786
PARK7
0.700 GeneticVariation UNIPROT DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. 23847046

2013
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT Human DJ-1 and its homologs are novel glyoxalases. 22523093

2012
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT Human DJ-1 and its homologs are novel glyoxalases. 22523093

2012
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT Human DJ-1 and its homologs are novel glyoxalases. 22523093

2012
dbSNP: rs774005786
rs774005786
PARK7
0.700 GeneticVariation UNIPROT Human DJ-1 and its homologs are novel glyoxalases. 22523093

2012
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. 19229105

2009
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. 19229105

2009
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. 19229105

2009
dbSNP: rs774005786
rs774005786
PARK7
0.700 GeneticVariation UNIPROT Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. 19229105

2009
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. 17846173

2007
dbSNP: rs74315351
rs74315351
PARK7
0.800 GeneticVariation UNIPROT Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. 17846173

2007
dbSNP: rs74315352
rs74315352
PARK7
0.800 GeneticVariation UNIPROT Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. 17846173

2007
dbSNP: rs774005786
rs774005786
PARK7
0.700 GeneticVariation UNIPROT Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. 17846173

2007
dbSNP: rs74315353
rs74315353
PARK7
0.810 GeneticVariation UNIPROT Analyzing the PARK7/DJ1 gene in 104 EOPD patients, we identified a third mutation, c.192G>C (p.E64D), associated with EOPD in a patient of Turkish ancestry and characterized the functional significance of this amino acid substitution. 15365989

2004